Our products leverage laser Doppler, Clark electrodes, and advanced signaling processing to deliver robust, noninvasive macrocirculation and microcirculation blood perfusion measurements. Because microcirculation is a valuable disease marker, our instruments have wide-reaching application in assessment, treatment planning, and research.
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Blood perfusion imaging helps determine best flap and identify flap ischemia early.
Assess the impact of injected or transdermally delivered drugs without impacting the process.
Early detection of complications in diabetic foot are crucial to prevent severe outcomes and save limbs.
Peripheral artery disease (PAD) affects over 113 million people globally, contributing to pain, disability, and, in severe cases, amputation. Early detection and accurate monitoring are critical for managing this chronic condition.
SPP is a noninvasive method that leverages laser Doppler to measure blood perfusion in the microcirculation. It is primarily used in clinical (and clinical research) settings to assess wound healing potential — especially in patients with chronic conditions such as diabetic foot.
Segmental limb pressure measurement is a noninvasive macrocirculation exam for evaluating blood perfusion in the limbs. It helps detect blockages or narrowing, making it invaluable for assessing peripheral artery disease (PAD) and end-stage PAD — chronic limb-threatening ischemia (CLTI).
Toe pressure and TBI are noninvasive macrocirculation measurements for evaluating blood perfusion in the toes, providing critical insight into vascular health. Toe pressure measurements are useful in wound healing, detecting and managing peripheral artery disease (PAD) and chronic limb-threatening ischemia (CLTI) — especially when ankle pressure may be unreliable due to noncompressible arteries.
Ankle pressure and ankle-brachial index (ABI) are noninvasive macrocirculation measurements for evaluating blood perfusion in the ankles, providing critical insight into vascular health. Ankle pressure measurements are the gold standard for assessing peripheral artery disease (PAD) in people without diabetes.
Finger pressure or digit-brachial index (DBI) is a noninvasive macrocirculation measurement.
Built on advanced signal processing and laser Doppler technology, our solutions provide comprehensive insights into macro- and microcirculation. They can be used in a range of clinical research applications, including dermatology, endothelial dysfunction, and exercise physiology. Our technologies are designed to facilitate data collection and generate robust insights that help clinical researchers deliver data-driven findings.
Preclinical researchers often face data collection challenges, like accuracy, repeatability, the need to translate data to clinical applications, and measurement tools that inadvertently introduce artifacts or stress responses in the models.
The CAM assay is a versatile animal model for studying tumor formation, angiogenesis, and metastasis.
Wound healing can be complex and unpredictable. Stakes are high when healing slows or stalls and every wound presents unique challenges. While foundational methods like visual inspections and touch tests like capillary refill are part of everyday practice, not all wounds respond the same.
The subcutaneous tumor model is a popular assessment system for in vivo evaluation of cancer medicine candidates. This model often uses immunodeficient animal strains, where cultured cancer cells are implanted subcutaneously, taking about two weeks to produce a solid tumor.
Microcirculation is crucial for delivering oxygen and nutrients to tissues and removing waste products. This fine-scale blood flow reflects underlying vascular health and is increasingly recognized as a sensitive marker of systemic diseases, including diabetes and peripheral artery disease (PAD).
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